| Chipotle Mexican Grill | Denver, Newport Beach | 13 de julho de 1993 |
| Chobani | Norwich | 2005 |
| CHS Inc. | Inver Grove Heights | 1931 |
| Church & Dwight | Ewing | 1846 |
| Circle | Boston | outubro 2013 |
| Cisco Systems | São José | 1984 |
| Citadel Enterprise Americas LLC | Miami | 1990 |
| Citgo | Houston | 1910 |
| Citizens Financial Group | Providence | 1954 |
| Citrix Systems | Fort Lauderdale | 1989 |
| Claris | Cupertino | 1987 |
| Clinique | Nova Iorque | 1968 |
| CodeGear | Scotts Valley, Califórnia | 2006 |
| Coinbase | São Francisco | 20 de junho de 2012 |
| Colgate-Palmolive | Nova Iorque | 1806 |
| Color Force | West Hollywood | 2007 |
| Comitê Nacional Democrata | Washington, D.C. | 1848 |
| Commonwealth Fusion Systems | Devens | 2018 |
| Complex | Nova Iorque | 2002 |
| Concord Music | Beverly Hills | 1973 |
| Conexant | Irvine | 1999 |
| Consol Energy | Pittsburgh | 1991 |
| Control Data Corporation | Bloomington | 1957 |
| Converse | Boston | 1910 |
| Coors Brewing Company | Golden | 1873 |
| CoreCivic | Nashville | 1983 |
| Costco | Issaquah | 1983 |
| CouchSurfing | São Francisco | 2 de abril de 2003 |
| Coverity | São Francisco | novembro 2002 |
| Crackle | Culver City | julho 2007 |
| Credo Reference | Boston | 1999 |
| CrossFit | Santa Cruz | 2000 |
| CrowdStrike | Austin | 29 de agosto de 2011 |
| Currier and Ives | Nova Iorque | 1835 |
| CVS Pharmacy | Woonsocket | 1963 |
| D'Addario | Farmingdale | 1973 |
| D23 | Burbank | 2009 |
| Dahon | Los Angeles | 1982 |
| Danelectro | Camarillo | 1947 |
| Danjaq LLC | Santa Mônica | 1962 |
| Databricks | São Francisco | 2013 |
| Datapoint | — | 1968 |
| DataStax | Santa Clara | abril 2010 |
| Dean Foods | Dallas | 1925 |
| Dean Guitars | Tampa | 1976 |
| Deckers Outdoor Corporation | Goleta | 1973 |
| Deep Space Industries | Mountain View | 22 de janeiro de 2013 |
| Dell | Round Rock | 7 de setembro de 2016 |